Biostatistics underpins the sound application of statistical methods in clinical research and encompasses the design of clinical trials (see Figure 1) and other quantitative research studies, and the analysis and reporting of data from such studies including inferences and the interpretation arising from them.
Our MISCH biostatisticians provide expertise in the following:
Design stage - Development of the research question(s), selection of study design, sample size calculation, study protocol, statistical analysis plan and ethics application;
Execution stage - Randomisation lists, database design and quality control of data collection procedures (including ethical handling of data);
Completion stage - Data cleaning and reproducible data processing, statistical analysis (especially where requiring skills to perform complex analyses using modern statistical techniques and software), preparation of written summaries (including graphical and tabular displays) of statistical analyses in a format suitable for publication in health-related journals or professional reports, including valid interpretation of statistical findings;
Translational stage - Interpretation and effective communication of research findings, leading to the development of policies and guidelines.