Adaptive Clinical Trials Designs: MelbourneEvent
The annual TEDMED event focuses on cutting-edge biomedical thinking, innovation in healthcare and large scale global public health opportunities across disciplines. Chaos+Clarity was the theme of this year’s conference, 14-16 November in Palm Springs, California. HISA members have special access to the recorded sessions now until 14 December 2018. If you are not a HISA member, remember that University of Melbourne staff and students are entitled to free individual membership under the University’s academic institution membership of HISA; to join, send an email from your unimelb address to firstname.lastname@example.org.News
This new online tool seeks to support researchers when completing checklists such as CONSORT and once filled in, generates the completed checklist which can then be used as part of the submission of a manuscript. It is hoped this tool will reduce the time and complexity of completing an EQUATOR checklist.News
Professor David Story, Director of MCATS, will be taking up the post of Interim Executive Director of the Melbourne Academic Centre for Health (MACH), starting 26 November 2018. Professor Julie Simpson will be taking over as the Director of MCATS during this time.The MACH is a National Health and Medical Research Council (NHMRC) recognised Advanced Health Research and Translation Centre (AHRTC).MACH is a member of the Australian Health Research Alliance (AHRA), which consists of all seven AHRTCs and two Centres for Innovation in Regional Health (CIRH).View the news item: https://www.machaustralia.org/new-interimNews
The Melbourne School of Population and Global Health held their annual awards this week with two MCATS academics recognised for their contributions to the school.Congratulations to Sabine Braat (on left) on her Leadership and Service Award. This award is in recognition of Sabine's achievements in improving the methodological rigour of clinical trials and growing the biostatistics capacity through the MCATS platform.Recognition was also given to Anurika De Silva (on right) for her former successes in the field of teaching and learning.News
Tuesday 9:00am - 4:30pmIntroduction to Cost Effectiveness analysis in HealthEvent
Practical Methods for Health Economic EvaluationEvent
REDCap training quarterly from February 2019News
See the NHMRC Guidelines & Publications for Australian Academic Clinical Trialists.News
"Clinical research is judged to be valid not by the results but how it is designed and conducted. The cliché of ‘do it right or do it over’ is particularly apt in clinical research." This publication is a great resource to help you organise and plan your research team.News
When Medicare was in early development, the goal was to provide affordable, basic health care to all Australians. But a new study has found Medicare spending is higher for children from high socioeconomic backgrounds than their poorer counterparts.News
The Lancet presents a Series of five papers about research.These papers set out some of the most pressing issues, recommend how to increase value and reduce waste in biomedical research, and propose metrics for stakeholders to monitor the implementation of these recommendations.News
Systematic reviews can be supported by the University of Melbourne Library Expert Search Service.News
From 14th February 2018 MCATS adopts new management framework.News
A policy forum recently re-examined and celebrated the 50th anniversary of a landmark speech by the former Prime Minister Edward Gough Whitlam.News
MCATS team member Sabine Braat describes randomised control clinical trials in the Conversation.News
New Health Informatics Fellowship Program opens in November 2017.News
MCATS team member and Biostatistics expert Sabine Braat explains clinical trials to us in the ConversationNews
MCATS can provide collaborative support for grant development and submission, and can provide expert advice within departmental panel grant pitch reviews. MCATS subscriptions are also available for data analysis, grant re-submission needs and project ideas development, in addition to EFT support for long term Department research needs (Biostatistics). Contact us through the MCATS project form, and review our collaboration agreement.
Access to researchers embedded within peer academic groups provides high standards of collaborative research support.View
Our program of courses and seminars covers study design, protocol development, REDCap and health economics.View
Research governance and ethics
There are a number of internationally recognised resources developed to support research.View
MCATS Research Journey
The MCATS Research JourneyView
The Melbourne Clinical and Translational Sciences (MCATS) research platform seeks to facilitate and collaborate, with our partners to ensure resources are visible and mechanisms are in place for accessing the core research methods of Biostatistics, Health Economics or Health Informatics. These areas are a necessity for good research design and governance in order to generate research findings that lead to improved health care and informed health service reform.
Biostatistics underpins the sound application of statistical methods in clinical research.View
Economic evaluation is widely used to assess many new health care interventions and technologies.View
Health informatics in the clinical and biomedical realm to aide in the optimal use of information. Includes REDCap.View
Research Quality and Integrity
Mutually beneficial relationships and resources allow the University and partners to work together, sharing resources and knowledge.View
MCATS overview and testimonials
I have a dataset I would like you to review, how do I prepare my data?
MCATS works collaboratively with SCC. A good summary can be found here
- I need to learn how to use REDCap
Do you have a brochure?
The MCATS brochure can be found here
If I pay for a service why would MCATS academics be on a publication?
MCATS is a collaborative research support platform where academics are funded for the work they provide. Aligning with academic collaborative principles, MCATS follows the University of Melbourne Authorship Policy (MPF1181) which states:
"5 Authorship. Introduction: The outcomes of research may be disseminated in a variety of ways but enduring forms, such as journal articles, are particularly important and to be an author for such a form is meritorious. To be named as an author, a researcher must have made a substantial scholarly contribution to the work and be able to take responsibility for at least that part of the work they contributed. Attribution of authorship depends to some extent on the discipline, but in all cases, authorship must be based on substantial contributions in a combination of:
- conception and design of the project
- analysis and interpretation of research data
- drafting significant parts of the work or critically revising it so as to contribute to the interpretation.
The right to authorship is not tied to position or profession and does not depend on whether the contribution was paid for or voluntary. It is not enough to have provided materials or routine technical support, or to have made the measurements on which the publication is based. Substantial intellectual involvement is required. A person who qualifies as an author must not be included or excluded as an author without their permission. This should be in writing, and include a brief description of their contribution to the work."
Do I have a say in who I will work with at MCATS with my successful grant?
Yes. Lead researchers will always have a say in which statisticans / health economists will be involved in a successful grant application, in particular the analysis stage.
The statistician who is the CI or AI on the grant application will act in the role of CI or AI similar to any other CI and AI on the grant after the grant is successful. This means that the statistician on the successful grant will be the primary contact person for the duration of the grant and he/she may supervise another statistician within MCATS who will do the analysis.
I am a researcher from the MMS, how do I access support?
The Melbourne Medical School (MMS) has invested in biostatistics support for two years Two new full-time MCATS staff members have been recruited for two years with the first commencing employment in May 2018, and the second starting in November 2018. Researchers with ideas or proposals that have been through departmental or peer review can enter their research information using the MCATS online portal.
Why do I need to pay for this work?
In an 'ideal world' this platform would be part of University Infrastructure and fully funded to provide services (free) to University researchers.
However at this time, MCATS is partially funded through a University of Melbourne Chancellery fund called the Melbourne Collaborative Research Infrastructure Program. This funding source requires cost recovery with funds reinvested into the platform and the goal to have a fully sustained business unit that does not require University investment.
What is the MCATS collaboration agreement?
The MCATS collaboration agreement is a plain english document that is pivotal to ensure all parties understand the process, needs, costs and expectations of the collaborative work. This in principle agreement is required by RIC and has been reviewed by the University lawyers for integrity.
The MCATS team has been developed to support high quality multidisciplinary research in basic science, cohort and epidemiological studies, clinical trials and health services research. This is enables through the provision of fundamental research components including Biostatistics, Health economics and Health informatics. MCATS also provides managment and networking capacities to coordinate and guide you through your project needs.
- Professor Julie Simpson
Interim Director of MCATS
Professor Simpson has over 20 years experience as a biostatistician contributing to clinical and population health research. Previously she has worked at St Thomas's Hospital, London, Mahidol-Oxford Research Programme in Thailand, University of Aberdeen, and Cancer Council of Victoria. Her main research areas are: the integration of biostatistics and mathematical modelling to improve the control of infectious diseases and statistical methods for handling missing data in observational cohorts. Julie is Head of the Biostatistics Unit, and Deputy Head of Melbourne School of Population and Global Health, and a NHMRC Senior Research Fellow and Chief Investigator of the NHMRC Centre of Research Excellence for Biostatistics.
- Professor David Story
Interim Director of MACH
Professor Story is the Foundation Chair of Anaesthesia at the University of Melbourne; and Head of the Anaesthesia, Perioperative and Pain Medicine Unit. His clinical work involves perioperative care for all surgical specialties including liver transplantation. David is a senior investigator with the Clinical Trials Network of the Australian and New Zealand College of Anaesthetists (ANZCA), sits on the ANZCA Research Committee, and is Deputy Chair of the ANZCA Safety and Quality Committee. His research is focused on effective approaches to reduce short term and long term perioperative risk, complications, disability, and mortality. He is committed to integrating research evidence and methodology into safety and quality in health care. David is working as the Interim Director of the MACH for 6 months until 26 May 2018.
- Professor Philip Clarke
Professor Clarke holds a Chair in Health Economics at the Melbourne School of Population and Global Health, University of Melbourne. His health economic research interests include developing methods to value the benefits of improving access to health care, health inequalities and the use of simulation models in health economic evaluation. He has also undertaken policy relevant research for the World Bank, OECD and AusAID.
- A/Professor Kathleen Gray
A/Professor Gray is the Acting Director of HABIc Dr Gray’s research interests include Public participation in health through new technologies: Patients’ and consumers’ use of web-based health information and communication, related health behaviours and health outcomes. Kathleen also has a keen interest in professional education for e-health including educational strategy and policy development involving building health informatics knowledge, skills and attributes required to improve e-health competence in the health workforce. She is involved in research impacts arising from new technologies and the integration of emerging high capacity broadband technologies in healthcare and biomedicine, and their potential influence on health literacy, health services and research communication.
- Associate Professor Douglas Iain Ross Boyle
A/Professor Boyle is the Director of the Research Information Technology Unit (R2). Since 2006 Doug has been researching, developing and implementing systems for the ethical acquisition of record-linkable data for audit, research and health surveillance. Consent management, security and privacy-protecting record linkage are key components and research areas. The software systems (GRHANITE™) are now responsible for the largest collections of record-linkable primary care data ever accumulated in Australia. Prior to emigrating from Scotland in 2006, Doug worked in a similar capacity to develop and implement technologies for wide-scale data acquisition. His system SCI-DC Network is internationally recognised and is playing a continuing key role in the support of population-based diabetes health service provision across Scotland.
- Dr Tanara Vieira Sousa
Dr Sousa is an MCATS Health Economist and Research Fellow at the Health Economics Unit from the Centre for Health Policy. She joined MCATS in July 2017. She has completed her PhD in Economics at the Federal University of Rio Grande do Sul/Brazil specialising in Health Economics. Tanara worked as a Researcher at the Center for Drug and Alcohol Research/Brazil for ten years, where she gained experience in Monitoring and Evaluation of alcohol and drugs related interventions, design analysis and reporting of observational studies in alcohol, drugs and road safety.
- Ms Sabine Braat
Ms Sabine Braat completed her postgraduate training in Belgium (Master of Science in Biostatistics preceded by Master in Applied Mathematics) following undergraduate study in mathematics. She has over 15 years’ experience working as a statistician in the pharmaceutical industry in the Netherlands where she contributed to the design, analysis and reporting of clinical trials ranging from the early clinical phases (Phase II) to post-marketing (Phase IV) in a range of medical areas. She joined MCATS in June 2015.
Dr An Duy Tran
Dr Tran is a Senior Research Fellow at the Health Economics Unit of the Centre for Health Policy. Before joining the University of Melbourne in October 2016, he was a Post-doc Researcher and Assistant Professor in Health Technology Assessment at the Maastricht University and Utrecht University in The Netherlands. Dr Tran’s expertise includes design of economic evaluation studies, analyses of costs and health outcomes, and development of computer models to simulate the impact of treatment strategies on progression of chronic diseases and assess the cost-effectiveness of the therapies. He joined MCATS in Jan 2017.
- Dr Anurika de Silva
Dr De Silva has a Bachelor of Science in Industrial Statistics from the University of Colombo, Sri Lanka. Her PhD in Biostatistics focused on multiple imputation methods for missing longitudinal data from the University of Melbourne. She worked as an Assistant Lecturer at the University of Colombo for 11 months (Sri Lanka) and conducted analyses of clinical trials during her PhD research. She joined MCATS in May 2018.
- Dr Audrey Poterie
Dr Poterie has a Bachelor of Science in Mathematics, a Master of Science in Mathematics Statistics from the University of Rennes and a Master of Science in Statistics from the Ecole Nationale Supérieure de la Statistique et de l’Analyse de l’Information (ENSAI) of Rennes (France). Her PhD in statistics and applied mathematics from the Institute for Research and Mathematics of Rennes (IRMAR), France focused on learning methods and on the elaboration of new machine learning algorithms. In addition, before her PhD she worked as a biostatistician at the Biostatistics and Epidemiology Unit in cancer research at the Gustave Roussy Institute (France) for 12 months between 2014 and 2015 and she did an internship at the Centre of Clinical Research and Effective Practice in Auckland for 2 months (New Zealand) in 2013. Audrey joined MCATS in November 2018.
Ms Sandra Henley-Smith
Ms Henley-Smith provides Health Informatics expertise to MCATS. Currently undertaking a Masters in Information Systems, Sandra has experience within the health industry and skills and experience in data collection methodologies, data collection tools and Case Record form design. Sandra also conducts the introduction to data management training workshops and has intricate knowledge of the REDCap data management system.
Dr Ronelle Welton
Dr Welton is the MCATS Manager. With a background in nursing, a PhD in Molecular Biology working with animal venoms' and a Masters in Public Health and Tropical Medicine, her work within both research and industry (international public health programs), gives Ronelle a strong track record in health program design, monitoring and evaluation, project management and governance.